Fast-acting and Safe Allergic Itch Relief For Your Dog

*Based on a model study for flea allergic dermatitis.
Apoquel Tablets are #1 in pet owner and vet satisfaction for oral medications for allergic dermatitis in dogs.*,6,7
Testimonials represent individual experience only and the experiences and opinions herein may be unique to the patient and the speaker. Individual results may vary considering the unique characteristics of the patient.
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Yes, you can use Apoquel for short periods.
Apoquel is labeled for use twice daily for up to 14 days, and then once daily for maintenance therapy. Speak with your vet on their recommendation for your dog.
Yes, Apoquel may be used with other treatment such as:4
Apoquel Tablet can be used before, after, or at the time of vaccination. The use of Apoquel Tablet in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents has not been evaluated. For dogs receiving these medications, pet owners should consult with their veterinarian about adding Apoquel Tablet to their dog’s treatment regimen.
The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of Apoquel. Your dog can continue to be treated with Apoquel as long as your veterinarian recommends. In a study, dogs were treated with Apoquel for more than two years.4
Yes, Apoquel Tablet can be given with or without food.
Please follow your veterinarian's prescription. Apoquel is labeled for use twice daily for up to 14 days, and then once daily for maintenance therapy. Speak with your vet on their recommendation for your dog.
Apoquel is also available as a chewable to make daily dosing even easier.
In a 10-year safety review, the most common individual side effects reported with Apoquel were vomiting, diarrhea, lethargy, anorexia, and bloodwork changes.9,10
If your dog is scratching, licking, or biting the same area repeatedly, the skin can become damaged, red, and sore. It’s a good idea to ask your dog’s veterinarian about the possible causes. It could be due to skin allergies, so your pet may require a prescription treatment such as Apoquel to treat the allergic itch. There also may be a skin infection that requires antibiotic or antifungal treatment from your veterinarian.
IMPORTANT SAFETY INFORMATION: See full Prescribing Information. Do not use Apoquel or Apoquel Chewable in dogs less than 12 months of age or those with serious infections. Apoquel and Apoquel Chewable may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel and Apoquel Chewable have not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel and Apoquel Chewable have been used safely with many common medications including parasiticides, antibiotics and vaccines.
INDICATIONS: Control of pruritus (itching) associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.
References:
Kynetec - PetTrak, US Pruritus Factored National. MAT Canine Pruritus, Total Unique Patients on Apoquel. Dec. 2023, Zoetis Inc.
Gadeyne C, Little P, King VL, Edwards N, Davis K, Stegemann MR. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 2014;25(6):512-518,e86. doi:10.1111/vde.12166.
Cosgrove SB, Wren JA, Cleaver DM, et al. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Vet Dermatol. 2013;24(5):479- e114. doi: 10.1111/vde.12047.
Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26(3):171-179, e35. doi: 10.1111/vde.12194.
Kynetec PetTrak – GAH-284: Unique Patient Count Since Launch Custom Report: Apoquel: January 2014 – February 2024.
Data on file, Apoquel/Cytopoint Vet Tracker Wave 18, 2024, Zoetis Inc.
ZMR: Apoquel, Apoquel Chewable & Cytopoint Dog Owner A&U Tracking Study: Wave 13 November 26, 2024
Data on file: Study Report A161C-US-21-C02, Zoetis Inc.
Nederveld SM, et al. Safety of the Selective JAK1 Inhibitor Oclacitinib in Dogs. J Vet Pharmacol Ther, 2025; 1-11, doi.org/10.1111/jvp.13503.
Data on file, A Ten-Year Post-Approval Safety Review for Apoquel® in the US (May 2013 to May 2023), Zoetis Inc.
Volume 6C Summary of the Product Characteristics: SPC European Commission, Brussels. 1 Vol. 6C. July 10, 2006, 1-11.